Clustered regularly interspaced short palindromic repeats are segments of prokaryotic DNA containing short, repetitive base sequences. These play a key role in a bacterial defence system, and form the basis of a genome editing technology known as CRISPR-Cas9 that allows permanent modification of genes within organisms. In a palindromic repeat, the sequence of nucleotides is the same in both directions. Each repetition is followed by short segments of spacer DNA from previous exposures to foreign DNA genes are located next to CRISPR sequences.
The CRISPR/Cas system is a prokaryotic immune system that confers resistance to foreign genetic elements such as those present within plasmids and phages that provides a form of acquired immunity. RNA harboring the spacer sequence helps Cas proteins recognize and cut exogenous DNA. Other RNA-guided Cas proteins cut foreign RNA. CRISPRs are found in approximately 40% of sequenced bacterial genomes and 90% of sequenced archaea.
A simple version of the CRISPRCas9, has been modified to edit genomes. By delivering the Cas9 nuclease complexed with a synthetic guide RNA into a cell, the cell's genome can be cut at a desired location, allowing existing genes to be removed and/or new ones added. The Cas9-gRNA complex corresponds with the CAS III crRNA complex in the above diagram.
NPS is a customer loyalty metric that measures customers’ willingness to not only return for another purchase or service but also make a recommendation to their family, friends or colleagues.
It is a powerful and effective technique, which can greatly increase a company's revenue if used properly.
The main advantages of NPS are close correlation with a company's growth and easy collection, interpretation and communication of the data.
Yes, it is.
Net Promoter Score is a number from -100 from 100.
Scores higher than 0 are typically considered to be good and scores above 50 are considered to be excellent.
The industry average for Health Care / Biotechnology: Biological Products (No Diagnostic Substances) is 0.
The final Net Promoter Score of a company strongly depends on a context in which the satisfaction is measured.
Consider an example: If CRISPR Therapeutics AG sends out NPS surveys immediately after purchase, they are tracking their customers' initial excitement and the checkout experience.
On the other hand, if they survey their customers a few weeks after the purchase they are also tracking how satisfied their customers are with their products and services over time.
Therefore, comparing the NPS score of CRISPR Therapeutics AG with your own without any further context is not that useful.
What is extremely useful though, is using the NPS methodology to track the satisfaction of your customers over time. That's where Customer.guru comes in.
|O2||Telecommunications / Wireless Carrier||7|
|Virgin Mobile UK||Telecommunications / Wireless Carrier||7|
|Verizon||Telecommunications / Cable/TV service||7|
|J.P. Morgan||Financial Services / Banking||8|
|Allianz||Financial Services / Banking||8|
|Visa||Financial Services / Credit cards||8|
|Sprint||Telecommunications / Wireless Carrier||5|
|NatWest Personal Banking||Financial Services / Banking||5|
|Goldman Sachs||Financial Services / Banking||5|
|Mastercard||Financial Services / Credit cards||5|
We have estimated the Net Promoter Score of CRISPR Therapeutics AG based on the publicly available information
including the sentiment of the company-related tweets, 3rd party reviews, and Alexa ratings.